James Franco and Seth Rogen are no longer on speaking terms
The actors, who have been friends for over 20 years, have reportedly not spoken to each other in over a year.
A source told Page Six that the split is due to Franco's alleged sexual misconduct.
In 2018, Franco was accused of sexual misconduct by several women. He has denied the allegations but has since settled with one of the women.
Rogen has not publicly commented on the allegations against Franco, but he has reportedly been distancing himself from him in recent months.
A source told Page Six that Rogen "doesn't want to be associated with someone who has been accused of such serious misconduct."
The split between Franco and Rogen is a major blow to their friendship, which has been one of the most enduring in Hollywood.
The two actors have starred in a number of films together, including "Freaks and Geeks," "Pineapple Express," and "The Disaster Artist."
They have also worked together on several projects outside of film, including the TV show "Sausage Party" and the video game "The Lego Movie."
The news of the split between Franco and Rogen has sent shockwaves through Hollywood.
Many are wondering if the two actors will ever be able to repair their friendship.